RNA Interference in Gene Regulation
Keywords:
RNA Interference, Gene Regulation, siRNA, Gene Silencing, Therapeutic StrategiesAbstract
This article investigates the role of RNA interference (RNAi) in regulating gene expression at the molecular level. Through a series of experiments, we demonstrate how RNAi can selectively inhibit gene activity, offering potential therapeutic strategies for genetic disorders. Our research provides insight into the mechanisms of gene silencing and highlights the therapeutic potential of RNAi in treating diseases caused by gene overexpression.
References
Sharma, V. K., Basu, S., & Chakraborty, S. (2015). RNAi mediated broad-spectrum transgenic resistance in Nicotiana benthamiana to chilli-infecting begomoviruses. Plant cell reports, 34(8), 1389-1399.
Sharma, V., Zheng, W., Huang, J., & Cook, D. E. (2020). CRISPR-Cas RNA targeting using transient Cas13a expression in Nicotiana benthamiana. In RNA Abundance Analysis: Methods and Protocols (pp. 1-18). New York, NY: Springer US.
