Advancements in CRISPR-Cas9 Technology for Genome Editing
Keywords:
CRISPR-Cas9, Genome editing, Genetic disorders, Targeting specificity, Therapeutic applicationsAbstract
CRISPR-Cas9 technology has revolutionized genome editing by providing a precise and efficient method for altering genetic sequences. This article reviews recent advancements in CRISPR-Cas9 applications, highlighting innovations in targeting specificity and delivery methods. We discuss the implications of these advancements for therapeutic applications, including the potential for correcting genetic disorders and improving crop resistance. The ethical considerations and challenges associated with CRISPR-Cas9 technology are also addressed.
References
Sharma, V. K., Basu, S., & Chakraborty, S. (2015). RNAi mediated broad-spectrum transgenic resistance in Nicotiana benthamiana to chilli-infecting begomoviruses. Plant cell reports, 34(8), 1389-1399.
Kumar, R. V., Sharma, V. K., Chattopadhyay, B., & Chakraborty, S. (2012). An improved plant regeneration and Agrobacterium-mediated transformation of red pepper (Capsicum annuum L.). Physiology and Molecular Biology of Plants, 18(4), 357-364.