Journal of Dentistry and Oral Health

Subcrestal vs. Equicrestal Implant Placement in Augmented Posterior Mandibular Sites: A Biomechanical and Histomorphometric Comparative Evaluation of Crestal Bone Stability and Osseointegration Kinetics

2026-06-25T14:09:37+03:00

Crestal bone preservation around dental implants placed in augmented posterior mandibular sites remains a clinically contested objective, with implant positioning depth representing a critical yet insufficiently standardized variable. This prospective comparative study evaluated subcrestal (1.5 mm) versus equicrestal implant placement protocols in 84 patients (168 implants) across a 24-month follow-up period. Primary outcomes included marginal bone level changes assessed by standardized periapical radiography and cone-beam computed tomography, while secondary outcomes encompassed implant stability quotient evolution, histomorphometric bone-to-implant contact ratios, and peri-implant soft tissue health indices. Subcrestal placement demonstrated statistically significant superiority in crestal bone maintenance (mean bone loss: 0.41 ± 0.12 mm vs. 0.89 ± 0.21 mm; p < 0.001) without compromising osseointegration kinetics or increasing peri-implant mucositis incidence. These findings advocate for protocol-specific implant depth selection contingent upon bone graft maturation staging and prosthetic emergence profile requirements.

A Paradigm Shift in the Understanding of Dental Caries: Re-evaluating the Role of Microbial Dynamics and Host Interactions

2026-09-08T14:43:25+03:00

Dental caries remains a leading global health issue, affecting billions worldwide despite extensive preventive strategies. This study conducted a cross-sectional analysis of oral biofilms from diverse patient demographics using advanced metagenomic sequencing techniques. Our findings reveal unexpected variations in microbial populations that correlate with carious lesions, highlighting the complex interplay between specific pathogens and host factors. Moreover, the study introduces a novel mathematical model to predict caries progression based on microbial community structure and patient-specific variables. These results challenge conventional paradigms by suggesting that microbial diversity rather than abundance plays a critical role in caries pathogenesis. This research underscores the need for a paradigm shift in caries management, focusing on personalized microbial ecology assessments.

Cementum-Derived Wnt/β-Catenin Crosstalk in Periodontal Ligament Mechanotransduction: Challenging the Tensional Homeostasis Doctrine in Alveolar Bone Remodeling

2026-06-25T14:00:43+03:00

The tensional homeostasis doctrine has long governed mechanobiological interpretations of periodontal ligament (PDL) adaptation; however, emerging evidence implicates cementum-derived Wnt/β-catenin signaling as an independent regulatory axis that fundamentally uncouples strain-mediated osteoblastogenesis from classical mechanotransduction cascades. This study investigated Wnt ligand secretion profiles in primary human cementoblasts under cyclic compressive loading (0.5–2.5 Hz), integrating RNA sequencing, immunofluorescence co-localization, and finite element modeling of alveolar socket stress distribution. Our findings demonstrate that cementoblast-specific Wnt3a upregulation suppresses RANKL-mediated osteoclastogenesis independently of integrin-focal adhesion kinase pathways, challenging prevailing dogma. These results reframe cementum not merely as an anchorage substrate but as an active mechano-endocrine interface governing periodontal osseous equilibrium, with significant implications for orthodontic force protocols and regenerative periodontal therapy.

A Comparative Analysis of Biomechanical Properties in Contemporary Dental Materials: Evaluating Their Longevity and Performance

2026-08-21T17:45:16+03:00

The advancement in dental materials has significantly influenced clinical outcomes in dentistry. This study aims to compare the biomechanical properties of various contemporary dental materials, focusing on strength, wear resistance, and biocompatibility. Utilizing a cohort of 120 dental specimens subjected to standardized mechanical stress tests, we employed advanced statistical methods to analyze the data. Preliminary findings indicate that composite resins exhibit superior wear resistance compared to traditional amalgams. Furthermore, flexural strength tests revealed that ceramic materials outperform both composites and amalgams under dynamic loading conditions, with a statistically significant difference (p < 0.05). This research not only bridges existing gaps in literature regarding material efficacy but also provides a foundation for future explorations in optimizing dental restorations.

Endodontic Microbiome Dysbiosis: An Empirical Analysis of Pathogenic Profiles in Apical Periodontitis Cases

2026-07-23T10:17:39+03:00

This study investigates the microbial profiles present in apical periodontitis, a common endodontic condition. Utilizing advanced sequencing techniques, we analyzed root canal samples from 100 patients undergoing endodontic treatment. The results reveal a distinct dysbiosis in microbial communities associated with clinical symptoms and periapical radiolucency. We identified several key pathogenic species contributing to the inflammatory response, including Enterococcus faecalis and Prevotella intermedia. These findings underscore the importance of microbiological assessment in guiding endodontic therapies and highlight potential targets for future therapeutic interventions.

A Case Study on the Efficacy of Bioceramic Sealers in the Retreatment of Non-Healing Endodontic Cases

2026-07-23T10:08:33+03:00

This article investigates the performance of bioceramic sealers in the retreatment of persistent endodontic infections. With the global increase in endodontic failures, bioceramic materials have emerged as potential candidates due to their favorable biological properties. We conducted a retrospective analysis of 150 patients who underwent endodontic retreatment using bioceramic sealers over a period of two years. The outcomes were evaluated based on clinical success and radiographic assessments. Our findings indicate a success rate of 85%, suggesting that bioceramic sealers provide a viable alternative for managing non-healing endodontic cases. This study contributes to the growing body of evidence supporting the use of bioceramic materials in dentistry, particularly in challenging clinical scenarios.

Optimization of Temporary Dental Materials for Enhanced Clinical Efficacy: Addressing the Shortcomings in Conventional Dental Practices

2026-09-08T14:47:53+03:00

The utilization of temporary dental materials is paramount in restorative dentistry, yet clinical inefficacies often result from suboptimal material properties. This study investigates the mechanical performance and biocompatibility of various temporary materials, including polymethyl methacrylate and composite resins, under simulated intraoral conditions. Employing a dual approach of quantitative tensile strength measurements and qualitative surface analysis via scanning electron microscopy (SEM), we demonstrated superior performance of a newly formulated resin composite compared to conventional materials. Results indicated a 30% improvement in tensile strength (p < 0.001) and enhanced biocompatibility attributes, suggesting a promising alternative for clinical applications. This research underscores the necessity for innovative solutions in temporary material selection, paving the way for improved patient outcomes in dental practices.

Finite Element-Optimized Biomechanical Framework for Angulated Implant Placement in Severely Resorbed Posterior Mandibular Ridges Using Platform-Switched Zirconia Abutments

2026-06-25T14:05:10+03:00

Severely resorbed posterior mandibular ridges present significant biomechanical challenges for osseointegrated implant systems, particularly regarding crestal bone stress distribution and long-term marginal bone stability. This study developed and validated a finite element analysis (FEA)-optimized placement protocol for angulated titanium implants (15°–25° off-axis) coupled with platform-switched zirconia abutments in class V–VI Cawood–Howell defect configurations. Forty-eight three-dimensional mandibular models were reconstructed from cone-beam computed tomography datasets and subjected to oblique and axial occlusal load simulations (150–400 N). Results demonstrated a statistically significant reduction in von Mises stress concentrations at the implant–abutment interface (p < 0.001) and a 31.4% decrease in periimplant cortical bone microdeformation compared to conventional non-angulated protocols. The proposed framework provides clinicians with quantitative angulation thresholds and abutment geometry parameters to optimize load distribution and minimize marginal bone resorption risk.

Addressing the Efficacy of Biomimetic Resin Composites in Minimally Invasive Dental Restoration: A Multi-Centric Evaluation

2026-08-21T17:49:53+03:00

The management of dental caries remains a prevalent challenge in oral health, necessitating innovative restorative materials. This study aims to evaluate the efficacy of biomimetic resin composites compared to conventional materials in minimally invasive dental restoration. A multi-center clinical trial was conducted across four dental facilities, involving 120 participants. The methodology employed a randomized controlled design, assessing restoration longevity, patient-reported outcomes, and clinical performance using established metrics. Results indicated a statistically significant improvement in restoration lifespan (p < 0.01) and patient satisfaction (p < 0.05) for biomimetic composites. This research underscores the potential of advanced materials in enhancing therapeutic outcomes in dentistry.

A Case Study on the Efficacy of Bioactive Glass in Treating Dentin Hypersensitivity: An Empirical Analysis

2026-08-21T17:40:35+03:00

Dentin hypersensitivity is a prevalent issue affecting a significant percentage of the population, leading to discomfort during routine activities such as eating and drinking. This study investigates the effectiveness of bioactive glass as a treatment modality for dentin hypersensitivity, leveraging a randomized controlled trial methodology involving 150 participants. Participants were divided into three groups: bioactive glass treatment, conventional fluoride varnish, and a control group. Pain perception was measured using a visual analog scale (VAS) at baseline, 1 week, and 4 weeks post-treatment. The results indicated a statistically significant reduction in hypersensitivity in the bioactive glass group compared to the fluoride group (p<0.05), with an average decrease in VAS scores reaching 60% at 4 weeks. These findings suggest that bioactive glass not only provides immediate relief but may also promote long-term desensitization through mineralization of dentin tubules. This study underscores the importance of innovative treatment approaches in managing dentin hypersensitivity effectively.

A Novel Framework for Multi-parameter Optimization in Dental Implant Surface Characterization

2026-07-23T10:13:13+03:00

The increasing demand for successful dental implants necessitates advanced methodologies for assessing and optimizing surface characteristics. This study introduces a novel framework that integrates multi-parameter optimization techniques to evaluate implant surface modifications, focusing on enhancing osseointegration and biomechanical stability. Utilizing a combination of experimental and computational approaches, we analyzed surface roughness, topography, and hydrophilicity, revealing significant correlations with cellular response in vitro. Our findings demonstrate that tailored surface characteristics can substantially improve clinical outcomes. This framework serves as a critical tool for future research and development in dental implant technology, offering a pathway towards personalized implant design. The implications of this research extend to enhancing patient-specific treatment plans and advancing the field of restorative dentistry.

Reassessing Paradigms of Periodontal Regeneration: A Meta-Analytical Critique of Current Clinical Practices

2026-09-08T14:52:18+03:00

Recent advancements in periodontal therapy have prompted a reevaluation of established concepts surrounding periodontal regeneration. This study employs a systematic meta-analysis of clinical trials from 2010-2023, evaluating the efficacy of novel biomaterials alongside traditional grafts. Our empirical methods revealed that the application of advanced biomaterials leads to a statistically significant improvement (p < 0.05) in periodontal attachment levels compared to conventional methods. Notably, the utilization of growth factor-enriched scaffolds demonstrates enhanced healing rates, suggesting a paradigm shift in therapeutic approaches. This research highlights the need for practitioners to adapt evidence-based strategies that optimize patient outcomes while addressing the emerging complexities in periodontal therapy. The findings underscore the critical role of ongoing research in redefining clinical paradigms within the field.